A review published in JAMA Network Open evaluated 41 RCTs of machine learning interventions. None of the studies fully followed CONSORT-AI standards, a set of guidelines developed for clinical trials evaluating medical interventions that include AI.

The consumer Internet began life in 1969 with four nodes, three in California and one in Utah. We know how the Internet changed how we shop, watch movies and travel. Our moonshot mission, which Dr. Anthony Chang has called a pediatric Internet made history in 2021 as we ended the year with four edge zones, two in California, one in Pennsylvania and one in Italy. We are only beginning to understand how it will transform children's healthcare, globally. Thank you for believing in the vision and helping turn it into a reality. One of the powers of the edge cloud is using digital twin applications to standardize data coming from the machines.